Recent advances in computing technology have enabled microsecond long all-atom molecular dynamics (MD) simulations of biological systems.Methods that can distill the salient features of such large trajectories are now urgently needed.Conventional clustering methods used to analyze MD trajectories suffer from various setbacks, namely (i) they are no
Emotion Induced Blindness (EIB) refers to the impairment in the identification of a neutral target image that follows a threatening or fearful distractor image.It has been suggested that valence plays a significant role in driving the perceptual impairment in EIB.Recent findings from the literature suggest that arousal has a very important role in
Cytotoxic T lymphocytes (CTLs) represent key immune effectors of the host response against chronic viruses, due High Rise Short to their cytotoxic response to virus-infected cells.In response to this selection pressure, viruses may accumulate escape mutations that evade CTL-mediated control.To study the emergence of CTL escape mutations, we employe
Anne-Catherine Maynard-Paquette,1 Claude Poirier,2 Carl Chartrand-Lefebvre,3,4 Bruno-Pierre Dubé2,5 1Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, Quebec, Canada; 2Centre Hospitalier de l’Université de Montréal (CHUM), Department of Medicine, Respiratory Medicine Division, Montreal,